ISSN 1662-4009 (online)

ey0017.1-7 | Hypopituitarism: Disease Modeling and New Discoveries | ESPEYB17

1.7. Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators

C Huisman , H Cho , O Brock , SJ Lim , SM Youn , Y Park , S Kim , SK Lee , A Delogu , JW Lee

To read the full abstract: Nat Commun. 2019 Aug 16;10(1):3696. doi: 10.1038/s41467-019-11667-y. PMID: 31420539.The hypothalamic arcuate nucleus (ARC) controls crucial physiological processes, such as growth, reproduction and energy homeostasis. However, it is unknown how ARC neurons gain their unique cellular identities and what are their developmental relationships. Here, the authors i...